Our Unique Approach to Angina & Coronary Heart Disease
Coronary heart disease (CHD) is a significant cause of mortality and disability worldwide. Our regenerative therapy targets damaged heart tissue directly — combining the proven benefits of physical rehabilitation with the regenerative and immunomodulatory power of mesenchymal stem cell therapy.
Coronary Heart Disease Overview
Coronary heart disease is a leading cause of mortality and disability globally. Regular physical activity plays a crucial role in maintaining heart muscle health, preserving vessel elasticity, reducing blood pressure, and enhancing physical balance and strength — forming the foundation of chronic disease management and cardiac rehabilitation programmes.
Our Regenerative Therapy Approach
Our regenerative therapy aims to effectively regenerate damaged heart tissue, going beyond symptom management to address the underlying structural damage caused by coronary disease. By combining physical rehabilitation with advanced cell-based therapies, we target improved mobility, flexibility, muscle strengthening, and long-term cardiac function.
MSC Properties & Cardiac Feasibility
Mesenchymal stem cells (MSCs), obtainable from various human tissues, possess multipotent and immunomodulatory characteristics that aid in tissue repair and help prevent unwanted immune responses. Extensive research has demonstrated the feasibility, safety, and efficacy of MSC-based therapy for cardiovascular diseases across multiple studies and clinical settings.
MSC Therapeutic Potential in Heart Disease
Although the precise mechanisms of MSCs are not yet fully understood, their therapeutic potential in treating ischemic diseases has been investigated in phase I/II clinical trials. MSCs hold promise as an effective strategy for both ischemic and non-ischemic cardiovascular disorders, offering a regenerative pathway where conventional treatments fall short.
References
Amyotrophic Lateral Sclerosis
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Shen, Z., Huang, W., Liu, J., Tian, J., Wang, S., & Rui, K. (2021c). Effects of mesenchymal stem Cell-Derived exosomes on autoimmune diseases. Frontiers in Immunology, 12. https://doi.org/10.3389/fimmu.2021.749192
Rheumatoid arthritis
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Systemic Lupus Erythematosus
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Multiple Sclerosis
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Masrori, P., & Van Damme, P. (2020). Amyotrophic lateral sclerosis: a clinical review. European Journal of Neurology, 27(10), 1918–1929. https://doi.org/10.1111/ene.14393
Sivandzade, F., & Cucullo, L. (2021). Regenerative stem cell therapy for Neurodegenerative Diseases: An Overview. International Journal of Molecular Sciences, 22(4), 2153. https://doi.org/10.3390/ijms22042153
IBD Inflammatory bowel disease
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Systemic vasculitis
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Liu, Y., Yan, L. M., Wan, L., Xiang, T. X., Le, A., Liu, J. M., … & Zhang, W. (2020). Viral dynamics in mild and severe cases of COVID-19. Cell & Bioscience, 10(1), 1-7. https://www.nature.com/articles/s41419-020-2542-9
Angina/Coronary Heart Disease
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Ulcerative Colitis
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Neurological conditions
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Parkinson’s
References
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Multiple system atrophy (MSA)
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Chronic traumatic encephalopathy
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Spinal cord injury
References
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Looi, Q. H., Eng, S. P., Liau, L. L., Tor, Y. S., Bajuri, M. Y., Ng, M. H., & Law, J. X. (2020). Mesenchymal stem cell therapy for sports injuries – from research to clinical practice. Sains malaysiana, 49(4), 825-838. https://doi.org/10.17576/jsm-2020-4904-12
Arthritis & Osteoarthritis
References
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