- Regeneration Clinic Treatments
Rheumatoid Arthritis
Our Method
Our Unique Approach to Rheumatoid Arthritis
Rheumatoid arthritis is a diverse inflammatory disease characterised by changes in the synovial tissue of joints, cartilage, and bone leading over time to joint dysfunction, deformity, and chronic pain requiring a multi-layered, targeted therapeutic approach.
Rheumatoid Arthritis Overview
Rheumatoid arthritis (RA) is a diverse disease categorised by a combination of genetic risk factors and autoantibodies. It is characterised by inflammatory changes in the synovial tissue of joints, as well as cartilage and bone, and in some cases other parts of the body leading to joint dysfunction, deformity, and chronic pain over time.
Disease Progression & Impact
The chronic inflammatory nature of RA drives progressive deterioration of joint structures. Persistent synovial inflammation erodes cartilage and bone, resulting in irreversible joint damage. Beyond the joints, RA can manifest in other systems of the body, underscoring the need for systemic therapeutic strategies that address both inflammation and tissue repair.
MSC Regenerative Properties
Mesenchymal stem cells (MSCs) possess significant potential to differentiate into various cell types, including adipocytes (fat cells), chondrocytes (cartilage cells), and osteoblasts (bone-forming cells) making them a powerful regenerative tool for restoring the joint tissues damaged by rheumatoid arthritis.
MSC Immunomodulatory Characteristics
Alongside their regenerative properties, MSCs exhibit unique immunomodulatory characteristics that offer new possibilities in the treatment of autoimmune diseases, including RA. These properties make MSCs a promising tool in stem cell-based therapies, targeting both the underlying immune dysregulation and the resulting tissue damage.