Spinal Cord Injury

Traumatic spinal cord injury (SCI) is a life-altering neurological condition that has significant socioeconomic implications for patients and their caregivers. While medical management of SCI has made considerable advancements in terms of diagnosis, stabilization, survival rates, and overall well-being of SCI patients, there has been limited progress in developing effective treatment options to improve neurological outcomes.

The secondary injury phase in the pathophysiology of SCI is a critical stage characterized by uncontrolled and destructive cascades involving molecular signaling, inflammation, vascular changes, and secondary cellular dysfunctions. Addressing this secondary injury is crucial for potential therapeutic interventions. One promising strategy that has been extensively tested is the use of mesenchymal stem cells (MSCs). MSCs have gained attention due to their ease of isolation and preservation, as well as their unique properties among other types and sources of stem cells.

Spinal cord injury

Citations and Scientific References

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