Peripheral Artery Disease

Peripheral artery disease refers to a group of diseases that affect arteries outside the heart and brain. The primary cause of peripheral artery disease is atherosclerosis, a condition characterized by the buildup of plaque in the arteries. Other less common causes include inflammatory disorders of the arterial wall, such as vasculitis, and noninflammatory arteriopathies like fibromuscular dysplasia.

Stem/progenitor cell-based therapy has emerged as a promising approach for treating various cardiovascular diseases, including myocardial infarction, stroke, peripheral arterial disease, and diabetes. A growing body of evidence from preclinical studies and clinical trials indicates that transplantation of stem/progenitor cells can replenish damaged cells, enhance cardiac and vascular functions, and promote tissue repair. These findings suggest the therapeutic potential of stem/progenitor cell transplantation in the treatment of peripheral artery disease and other cardiovascular conditions.

Peripheral Artery Disease

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