Cardiovascular Conditions

Cardiovascular diseases (CVDs) are a group of disorders affecting the heart and blood vessels and are a leading cause of death and disability worldwide, as reported by the CDC. Hypertension, commonly known as high blood pressure, is a major risk factor for CVD and is responsible for over 10 million deaths annually worldwide.

Mesenchymal stem cells (MSCs) possess certain characteristics that make them suitable for potential use in treating cardiovascular conditions. These cells can be amplified and renewed in laboratory settings, have low immunogenicity (low chance of causing an immune response), and exhibit immunomodulatory properties. Furthermore, MSCs can differentiate into various cell types under specific conditions.

In the context of the cardiovascular system, MSCs have shown promise in myocardial protection. They can reduce inflammation levels, encourage the differentiation of myocardial cells around areas of heart damage and promote angiogenesis (the formation of new blood vessels). Additionally, MSCs can enhance resistance to cell death (apoptosis) and inhibit fibrosis, making them desirable for cardiovascular repair. Preclinical studies have demonstrated the transplantation of MSCs to be beneficial in improving cardiac repair.

Cardiovascular disease

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